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Interactions

A. Top Drug-Drug Interactions:

1.Nitrates (e.g., nitroglycerin, isosorbide dinitrate): Cialis and nitrates both lower blood pressure. Taking them together can cause a significant and potentially life-threatening drop in blood pressure (hypotension), leading to dizziness, fainting, or even heart attack or stroke. It is contraindicated to use Cialis with nitrates or recreational "poppers" (amyl nitrites).

2.Alpha-blockers (e.g., prazosin, terazosin, tamsulosin): Both Cialis and alpha-blockers relax blood vessels, which can lead to excessive blood pressure reduction when used together. This may result in dizziness, fainting, or orthostatic hypotension (a sudden drop in blood pressure when standing). If needed, your doctor may adjust the dosage or recommend spacing the medications.

3.Other antihypertensive drugs (e.g., atenolol, propranolol, enalapril, lisinopril): Cialis can enhance the blood-pressure-lowering effects of these medications. While this interaction is usually less severe than with nitrates or alpha-blockers, it can still cause dizziness or fainting in sensitive individuals. Close monitoring of blood pressure is recommended.

Other Drug-Drug interactions:

  • Ketoconazole, itraconazole (used to manage fungal infection)
  • Protease inhibitors (used to manage HIV infection) Ex. ritonavir, lopinavir
  • Phenobarbital, phenytoin, carbamazepine (medicines used for fits)
  • Rifampicin, erythromycin, clarithromycin (medicines used for bacterial infections)
  • Other medicines used to improve blood flow to the penis (Ex. sildenafil)

B. Drug-Food Interactions:

Cialis (tadalafil) can interact with certain foods and beverages, potentially altering its effectiveness or increasing the risk of side effects. Here are the key drug-food interactions to be aware of:

  1. Grapefruit and Grapefruit Juice: Grapefruit can increase the levels of tadalafil in your blood by interfering with its metabolism. This may amplify side effects, such as headaches, dizziness, or low blood pressure. Avoid consuming grapefruit or grapefruit juice while taking Cialis.
  2. Alcohol: Drinking alcohol with Cialis can enhance the blood pressure-lowering effects of the medication, leading to symptoms like dizziness, lightheadedness, or fainting. Limiting alcohol intake is recommended while using Cialis.
  3. High-Fat Meals: While Cialis can be taken with or without food, consuming it with a high-fat meal may delay its onset of action. Opt for lighter meals if rapid effectiveness is needed.
  4. Caffeine: Though not a direct interaction, combining Cialis with high caffeine intake might worsen side effects like headaches or increase heart rate in sensitive individuals.
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Important Considerations:

  • Cialis is not suitable for use in individuals with certain health conditions or when the medication is being used in combination with other medications.
  • Use with caution in individuals using medications that may affect blood pressure or with uncontrolled blood pressure or potassium levels.
  • Cialis should not be used by individuals with severe liver disease.
  • Cialis should not be used by individuals with a known sensitivity to tadalafil or with any condition that may increase the risk of cardiovascular events.
  • Cialis is not suitable for use in individuals with a uncontrolled blood pressure.
  • Cialis is a prescription medication and should only be used under the supervision of a healthcare provider.

References:

Fungal Interactions

This document contains some literature on drug-drug interactions involving tadalafil and other bioactive substances. It is not intended in all cases or for treatment of all types of fungal infections. See also the.

Description

Cialis (Tadalafil)

Cialis (Tadalafil) is a popular medication used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). It is a phosphodiesterase type 5 (PDE5) inhibitor, which helps to relax and widen blood vessels, improving blood flow to particular areas of the body, such as the penis, to improve sexual performance and stimulate the natural healing process in the lungs and prostate. Cialis works by increasing blood flow to the penis, helping men to achieve and maintain an erection. It can be taken orally or applied topically, depending on your preference and how you are feeling. Cialis is available in different strengths and dosage forms:

  • 20mg
  • 40mg
  • 60mg

It is important to follow your healthcare provider’s instructions when taking Cialis. Common side effects may include headache, flushing, nasal congestion, upset stomach, and visual disturbances. If you experience any severe or persistent side effects, please consult with your healthcare provider. We recommend that you contact your doctor immediately.

Cialis can be taken with or without food, but should be taken on an empty stomach. You should also avoid taking Cialis with dairy products, calcium-fortified juices, or dairy products that contain gluten. It is also important to avoid grapefruit juice or alcohol while taking Cialis. It is also important to drink plenty of fluids while taking Cialis, as it may increase the risk of dizziness and drowsiness.

Side effects of Cialis (Tadalafil)

Most side effects are temporary, lasting a few days to weeks. However, if they are severe or persistent, please consult your healthcare provider.

The most common side effects reported by men taking Cialis include headache, dizziness, back pain, flushing, nasal congestion, and vision changes. If any side effects do occur, please let your doctor know.

If you experience any serious side effects, please contact your healthcare provider.

Precautions when taking Cialis (Tadalafil)

Before taking Cialis, you should inform your healthcare provider if you have a history of liver or heart disease, heart failure, or any other medical conditions. Cialis is not recommended for use by pregnant or breastfeeding women. It is also not recommended for women who are breastfeeding. Women should not handle crushed or broken Cialis tablets. Cialis is not recommended for children under the age of 18, pregnant or breastfeeding women, or people who are taking any other medicines. If you have any questions about how to take Cialis or Cialis-related tablets, please consult your healthcare provider for guidance.

Storage Instructions

Keep Cialis tablets in their original packaging, tightly closed, and out of reach of children. Store Cialis tablets in a cool and dry place, away from direct sunlight. Store Cialis tablets at temperatures between 40°C and 77°C (104°F to 111°F).

It is not recommended to keep Cialis in your car until you know how it will react. Cialis tablets should be stored in a cool, dry place, away from direct sunlight. If you want to keep Cialis, read the label carefully, use a consistent schedule, and store the tablets in a cool dry place, away from direct sunlight. Avoid storing Cialis in the bathroom or in the car.

Cialis (Tadalafil) is a phosphodiesterase type 5 (PDE5) inhibitor. It is used to treat erectile dysfunction (ED), benign prostatic hyperplasia (BPH), and pulmonary arterial hypertension. It works by relaxing the blood vessels in your penis, allowing increased blood flow, and improving the ability to achieve and maintain an erection. Cialis belongs to a class of drugs called phosphodiesterase type 5 (PDE5) inhibitors. It is used to treat erectile dysfunction (ED) in men. It works by increasing blood flow to the penis, helping to achieve and maintain an erection.

No. People do it, but getting it through Customs without it being confiscated depends on which agent interviews you upon arrival back in the US.

The Food and Drug Administration policy on theimportation of prescription drugspurchased abroad is fairly clear.

Under most circumstances,federal guidelines prohibit the importation of such drugs for personal use, largely because medications sold in another country have not been approved by the FDA for use in this country.

Importation of Prescription Drugs for Personal Use

That said, your personal experience in returning to the United States with or another prescription drug you’ve purchased abroad depends to a very large extent on the Customs agent who checks your baggage upon your return.

If you’ve been honest in filling out your Customs declaration and have listed the foreign-bought medications, Customs legally could seize the drugs. However, the tendency is to look the other way if the drug in question is not a controlled substance and if the amount purchased doesn’t exceed a 90-day supply.

Certain Drugs Are Allowed

do allow thepersonal importation of prescription drugs that treat serious medical conditionsand that aren’t available in the United States.

However, there are a few other conditions that govern the policy on such drugs.

  • The medication must not pose an unreasonable risk.
  • You must attest — in writing — that the drug is strictly for your personal use.
  • The amount of drug brought into the country should not exceed a three-month supply. If the drug is to be taken twice daily, that would mean no more than 180 units would be allowed.

Risk of Prescription Drugs being Confiscated by United States Customs

The FDA’s guidelines apply toprescription medications that are brought in from any country outside the United States, including Canada.

While most over-the-counter medications can be imported in amounts consistent with personal use, this policy does not extend to products that are OTC in other countries but available only by prescription in the United States.

The bottom line: Be aware that you’re running arisk of confiscation when you return to the United States with prescription drugsbought abroad.

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Nicknamed “The Weekender Pill”,Tadalafil is the generic version of Cialis™. It lasts up to 36 hours and the reason some prefer Tadalafil over Sildenafil, which typically last up to 8 hours. Please select your preferred dosage and number of pills.

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For your first order with us, after placing an order, you will be prompted to upload your ID and submit our health questionnaire, soour physician canreview your basic health information,in order to mail prescription medications. You will not need to do this for refill orders.

Disclaimer:This is not medical advice. You and our physician will determine if (and potentially how) you should take Tadalafil. Please consult with your physician if you have any further questions.For more information on Tadalafil,.

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Our physician will review your health questionnaire

All medications have some role in improving your sexual health.

Alcohol

metabolism: To reduce the absorption of alcohol, the drug.

tadalafil 20mg: The tablet contains 5mg of tadalafil and lasts for up to 36 hours. It does not require any additional time before being available for use.

tadalafil 5mg: The tablet contains 5mg of tadalafil and lasts for up to 6 hours.

tadalafil 10mg: The 10mg tablet contains 10mg of tadalafil and lasts for up to 10 hours.

: The 20mg tablet contains 10mg of tadalafil and lasts for up to 20 hours.

Precautions

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